What is ALS, Illness which Sandra Bullock's Partner Bryan Randall had?

 It is so heartbreaking to hear Sandra Bullock's partner Bryan Randall lost his life at 57. So, I decided to search for Amyotrophic Lateral Sclerosis (ALS). Whether ALS is avoidable, its symptoms, and its causes, are all covered in this article.


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What Are ALS Symptoms?

People with ALS symptomps have a substantial lack of muscle control and it grows worse with time. The symptoms of ALS include muscle twitching, limb weakness, trouble speaking, may experience problems walking, stumbling, and weakness in the knees, ankles, and hands. It gradually impairs muscular control and affects a person's capacity for breathing, moving, speaking, and eating. According to the MayMayo Clinic, ALS is a neurological illness that affects neurons in the spinal cord and the brain. 

Although ALS cannot be cured, you may reduce the disease's progress.

What Is ALS Cause?

Although ALS is an unknown cause illness, it is a progressive neurological disorder. However, it is thought that the development of the condition is influenced by both genetics and factors from the environment. Recent research shows a connection between severe mental illnesses and ALS.

Can ALS Be Prevented?

One cannot stop ALS.1 However, scientists have discovered that carotenoids, a pigment present in plants, may assist in either preventing or postponing the onset of neurodegenerative illnesses like ALS.

What are Carotenoids?

Orange, red, green, and yellow pigments found in fruits and vegetables are called caroteno Carotenoids. Green leafy foods including broccoli, kale, spinach, and coriander have high levels of carotenoids.3

Inflammation is brought on by oxidative stress, which is brought on by the body's increasing amounts of free radicals. Antioxidants, which slow down or stop cell damage in your body, include carotenoids.4

The nerves that instruct muscles to contract are inflamed and destroyed in ALS. Carotenoids can aid in the prevention of neuroinflammation, according to research.5

 It would not be shocking that disturbances of the nervous system can cause cognitive, psychological, motivational, and behavioral dysfunction. 

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References:

1. Centers for Disease Control and Prevention. Amyotrophic lateral sclerosis (ALS).

2. Fitzgerald KC, O’Reilly ÉJ, Fondell E, et al. Intakes of vitamin c and carotenoids and risk of amyotrophic lateral sclerosis: pooled results from 5 cohort studies. Ann Neurol. 2013;73(2):236-245. doi:10.1002/ana.23820

3. Cho KS, Shin M, Kim S, et al. Recent advances in studies on the therapeutic potential of dietary carotenoids in neurodegenerative diseases. Oxid Med Cell Longev. 2018;2018:4120458. doi:10.1155/2018/4120458

4. National Center for Complementary and Integrative Health. Antioxidants: in depth.

5. Lakey-Beitia J, Kumar D. J, Hegde ML, et al. Carotenoids as novel therapeutic molecules against neurodegenerative disorders: chemistry and molecular docking analysis. Int J Mol Sci. 2019;20(22):5553. doi:10.3390/ijms20225553

6. Yaron A, Schuldiner O. Common and divergent mechanisms in developmental neuronal remodeling and dying back neurodegeneration. Curr Biol 2016;26:R628–R639.

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